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lrpC [2020-10-27 12:17:59]
sequence-independent DNA-binding and DNA-bending protein (Lrp family), facilitates the formation of higher order protein-DNA complexes
function
DNA repair/ recombination
product
DNA-binding and -bending protein
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination][category|SW 3|Information processing] → [category|SW 3.1|Genetics] → [category|SW 3.1.5|DNA repair/ recombination] → [category|SW 3.1.5.6|Other proteins]Gene
Coordinates
476,059 476,493
The protein
Protein family
([SW|Lrp family])[SW|Domains]
[SW|HTH asnC-type domain] (aa 3-64) (according to UniProt)Structure
[PDB|2CFX] [pubmed|16528101]Expression and Regulation
Operons
genes
[gene|AC2618C53DA020F2CD5192AEE462D15E8EE0F57F|lrpC]-[gene|7D5327BD1DD5FD5F90B2C849589923AA3D8B20EF|topB]
description
[pubmed|22383849]sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [pubmed|10913073], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]view in new tabadditional information
50 ... 300 molecules per cell [PubMed|10913073]Biological materials
Mutant
MGNA-C106 (ydaI::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2104 NBRP B. subtilis, Japan]BKE04250 ([gene|AC2618C53DA020F2CD5192AEE462D15E8EE0F57F|lrpC]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE04250 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTCAACATCCTTCTTTT, downstream forward: _UP4_TAGAGAGTGCCGCGCGAAGTBKK04250 ([gene|AC2618C53DA020F2CD5192AEE462D15E8EE0F57F|lrpC]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK04250 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTCAACATCCTTCTTTT, downstream forward: _UP4_TAGAGAGTGCCGCGCGAAGTReferences
9341680,10913073,16407330,10606655,12458218,16528101,16528101